- Dairy Consultants, Shelbyville
- Dance Companies, Shelbyville
- Decorating & Designing Services, Shelbyville
- Delicatessen Restaurants, Shelbyville
- Dental Bonding & Cosmetic Dentistry, Shelbyville - Cosmetic Dentist & Tooth Bonding
- Dentists, Shelbyville
- Department Stores, Shelbyville
- Dermatologists, Shelbyville - Skin Doctors, Physicians & Surgeons (Dermatology)
- Developmental Children Services, Shelbyville
- Dialysis Clinics, Shelbyville - Kidney Dialysis Centers
- Digital Imaging Photographers, Shelbyville
- Diner Restaurants, Shelbyville
- Disciples Of Christ Church, Shelbyville
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- Discount Stores, Shelbyville - Clothing, Grocery, Furniture, Etc
- Dispensing Machines, Shelbyville
- Divorce & Family Law Attorneys & Lawyers, Shelbyville
- Doctors, Physicians & Surgeons, Shelbyville
- Donuts, Shelbyville
- Dressmakers Supplies, Shelbyville
- Drinking Establishments, Shelbyville
- Drive In Restaurants, Shelbyville
- Drivers License Testing, Shelbyville
- Drugs, Pharmaceutical Products & Toiletries - Wholesale & Manufacturers, Shelbyville
- Dry Cleaning & Laundry, Shelbyville - Dry Cleaners
- Drywall, Insulation & Plaster Contractors, Shelbyville - Installation & Repair Services
- Dumpster Rental, Shelbyville
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