- Obstetricians & Gynecologists, Noblesville - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Office Supplies, Equipment & Office Furniture Stores, Noblesville
- Oil & Gas Companies, Noblesville
- Oil Change & Lubrication, Noblesville - Auto Oil & Quick Lube
- Oncologists, Noblesville - Cancer Doctors, Physicians & Surgeons (Oncology)
- Ophthalmologists, Noblesville - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Noblesville
- Optometrists, Noblesville - Eye Doctors, Physicians & Surgeons (Optometry)
- Ornamental Greenhouses, Noblesville
- Ornamental Nursery, Noblesville
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- Ornamental Nursery Services, Noblesville
- Orthodontist, Noblesville - Teeth Straightening, Invisalign & Dental Braces
- Orthopedists, Noblesville - Orthopedic Surgery Doctors, Physicians & Surgeons
- Other Attorneys & Lawyers, Noblesville
- Other Building Materials & Supplies, Noblesville
- Other Lawyers & Attorneys, Noblesville
- Outdoor & Lawn & Garden Equipment Repair & Service, Noblesville
- Outdoor Equipment & Accessories, Noblesville
- Outpatient Services, Noblesville - Outpatient Care
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