- Sand Gravel & Aggregate, Tell City
- Sandwich Shop Restaurants, Tell City
- Satellite Dish Antennas & Equipment Dealers, Tell City
- Satellite TV Service, Tell City
- Screen Printing, Tell City
- Seafood Restaurants, Tell City
- Secretarial School, Tell City
- Security Brokers & Dealers, Tell City
- Senior Citizens Service & Health Organizations, Tell City
- Septic Tanks & Systems, Tell City - Wholesale, Dealers & Suppliers
- Sewer & Drain Cleaning & Repair, Tell City - Drain Cleaner & Installation Services
- Sheet Metal Contractors, Tell City - Sheet Metal Fabrication
- Sheet Metal Fabricators & Ductwork Contractors, Tell City
- Shoe Stores, Tell City - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Tell City
- Skin Care & Cosmetology Salons, Tell City
- Skin Care Products & Treatments, Tell City
- Sleep Doctors, Tell City - Specialists, Physicians & Surgeons (Sleep Medicine)
- Social Services & Welfare, Tell City
- Solar Equipment, Tell City
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- Special Needs Transportation, Tell City
- Specialty Animal Services, Tell City
- Specialty Stores, Tell City
- Speech & Hearing Specialists, Tell City
- Speech Pathologists, Tell City - Speech & Language Therapy
- Sporting Goods Stores, Tell City
- Sports Bars & Lounges, Tell City
- Staffing & Support Services, Tell City
- State Government, Tell City
- Steak House Restaurants, Tell City
- Stocks & Bond Brokers, Tell City
- Stone, Tell City
- Stone & Rock Quarry, Tell City - Gravel Pit, Shale, Granite, Limestone, Crushed Rock, etc
- Stone Setting Contractors, Tell City
- Stoves & Furnace Equipment, Tell City - Fittings & Repair Parts
- Substance Abuse Clinics, Tell City - Alcoholism, Addiction & Drug Abuse Treatment Centers
- Swimming Pool, Sauna & Spa Contractors, Tell City
- Swimming Pools Contractors, Tell City - Install Inground - Above Ground Pools
- Swimming Pools Supplies, Equipment & Accessories, Tell City
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