- Carpet Rug & Upholstery Cleaners, Roanoke
- Carpet, Rug & Linoleum Flooring Dealers, Roanoke
- Cars, Truck, Van & SUV Car Dealerships, Roanoke - Auto Dealers
- Casual Dining Restaurants, Roanoke
- Caterers Food Services, Roanoke
- Catholic Churches, Roanoke
- Cellular & Mobile Phone Service, Roanoke
- Child Care & Day Care Services, Roanoke
- Christian Churches, Roanoke
- Churches 1 Of 3, Roanoke
- City & County Administrative Agencies, Roanoke
- City & County Government, Roanoke
- Cleaning & Maintenance Services, Roanoke
- CNC Machine Shop, Roanoke
- Commercial Printing, Roanoke
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- Commercial Printing Manufacturers, Roanoke
- Communications Services, Roanoke
- Community & Recreational Facilities, Roanoke
- Community Services, Roanoke
- Computer & Audio Visual Services, Roanoke
- Computer & Laptop Repair, Roanoke - PC Repair Services
- Computer & Software Stores, Roanoke
- Computer Repair, Roanoke
- Computer Software & Services, Roanoke
- Computer Software Service, Roanoke
- Computer System Consultants, Roanoke - IT Consulting Services
- Construction, Roanoke
- Consultants & Services, Roanoke
- Convenience Stores, Roanoke
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