- U-Haul Truck Rental, Merrillville - U-Haul Moving
- U-Haul Trucks, Merrillville - Uhaul Truck Rental
- U.S. Postal Service, Merrillville
- Underground Utility Locating Service, Merrillville
- Unfinished Furniture, Merrillville
- Unfurnished Apartments, Merrillville
- Uniforms, Merrillville
- Uniforms, Work Clothes & Safety Clothing, Merrillville
- United States Marines, Merrillville
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- Unsupported Plastic Film & Sheet Manufacturers, Merrillville
- Upholstery Fabric Stores , Merrillville
- Urologists, Merrillville - Urology Doctors, Physicians & Surgeons
- Used Book Stores, Merrillville - New & Rare Books
- Used Cars, Truck, Van & SUV Car Dealerships, Merrillville
- Used Merchandise, Resale Shops & Thrift Stores, Merrillville
- Used Motorcycle Dealers, Merrillville
- Utilities, Merrillville
- Utility & Waste Management Services, Merrillville
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