- Safe & Vault, Martinsville
- Sand Gravel & Aggregate, Martinsville
- Sandwich Shop Restaurants, Martinsville
- Satellite Dish Antennas & Equipment Dealers, Martinsville
- Satellite TV Service, Martinsville
- Sawmill & Planing Mills, Martinsville
- Sawmill Supplies & Equipment Repair, Martinsville
- Scientific & Laboratory Equipment & Instruments, Martinsville
- Screen Printing, Martinsville
- Seafood Restaurants, Martinsville
- Secondary Schools, Martinsville
- Security & Commodity Brokers, Martinsville
- Security Alarm Systems - Home & Business, Martinsville
- Security Brokers & Dealers, Martinsville
- Security Control Systems & Monitoring, Martinsville - Polygraph, Lie Detector, CCTV, Fire Sensor Equipment, Etc
- Security Services, Martinsville
- Semiconductors & Equipment, Martinsville
- Senior Citizens Service & Health Organizations, Martinsville
- Septic Tank Installation & Repair, Martinsville - Septic Systems
- Septic Tank Pumping & Cleaning, Martinsville - Septic Systems
- Septic Tanks & Septic Systems Contractors, Martinsville - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Septic Tanks & Systems, Martinsville - Wholesale, Dealers & Suppliers
- Service Establishment Supplies & Equipment, Martinsville
- Sewer & Drain Cleaning & Repair, Martinsville - Drain Cleaner & Installation Services
- Sewing & Yarn Stores & Supplies, Martinsville
- Sharpening Service, Martinsville
- Shoe Stores, Martinsville - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Martinsville
- Siding Contractors, Martinsville - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
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- Signs, Martinsville
- Snacks & Desserts, Martinsville
- Social Service Organizations Volunteer Services, Martinsville
- Social Services & Welfare, Martinsville
- Societies & Foundation Associations, Martinsville
- Special Coatings, Martinsville - Protective Coatings
- Special Dies Tools Jigs & Fixtures Manufacturers, Martinsville
- Special Interest Schools Or Instruction, Martinsville
- Specialty Animal Services, Martinsville
- Specialty Stores, Martinsville
- Speech & Hearing Specialists, Martinsville
- Sporting Goods Stores, Martinsville
- Sports Medicine, Martinsville - Doctors, Physicians & Surgeons
- Sprinkler Alarm Systems, Martinsville - Fire Sprinkler Systems
- State Government, Martinsville
- Steak House Restaurants, Martinsville
- Steel & Metal Goods, Martinsville - Steel Distributors
- Steel Detailers, Martinsville
- Steel Manufacturers, Martinsville
- Steel Work Contractors, Martinsville
- Stock & Bond Brokers & Dealers, Martinsville
- Stocks & Bond Brokers, Martinsville
- Submarine Sandwich Restaurants, Martinsville
- Support Services, Martinsville
- Surveyor Services, Martinsville - Surveying Service
- Swimming Pool, Sauna & Spa Contractors, Martinsville
- Swimming Pools Contractors, Martinsville - Install Inground - Above Ground Pools
- Swimming Pools Supplies, Equipment & Accessories, Martinsville
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