- Salvage Yards, Junk Yards & Wrecker Service, East Chicago
- Salvation Army, East Chicago
- Sandwich Shop Restaurants, East Chicago
- Satellite Dish Antennas & Equipment Dealers, East Chicago
- Savings & Loan Associations, East Chicago
- Savings Banks, East Chicago
- School - Catholic, East Chicago
- School - Christian, East Chicago
- Scientific & Laboratory Equipment & Instruments, East Chicago
- Scrap & Waste Machinery, East Chicago
- Scrap & Waste Materials, East Chicago
- Seafood Restaurants, East Chicago
- Seals Notary & Corporation, East Chicago
- Secondary Schools, East Chicago
- Security Investigative Services, East Chicago
- Security Services, East Chicago
- Semi Precious Metals, East Chicago
- Shock Absorber, East Chicago
- Shock Absorbers & Struts, East Chicago
- Shoe Stores, East Chicago - Mens, Womens & Kids Shoes
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- Shopping & Shopping Services, East Chicago
- Signs, East Chicago
- Slag, East Chicago
- Social Clubs & Organizations, East Chicago
- Social Services & Welfare, East Chicago
- Social Workers & Services, East Chicago
- Societies & Foundation Associations, East Chicago
- Specialty Stores, East Chicago
- Sporting & Recreational Camps, East Chicago
- Sporting Goods Stores, East Chicago
- State Government, East Chicago
- Steel & Metal Goods, East Chicago - Steel Distributors
- Steel Fabrication & Processing Equipment, East Chicago
- Steel Manufacturers, East Chicago
- Steel Mills & Blast Furnaces, East Chicago
- Steel Treatment, East Chicago
- Steel Treatment, East Chicago
- Storage Containers, East Chicago
- Substance Abuse Clinics, East Chicago - Alcoholism, Addiction & Drug Abuse Treatment Centers
- Sweepers & Scrubbers Industrial, East Chicago - Sweeping Service
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